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Du Pasquier, L. (1982). Antibody diversity in lower vertebrates—why is it so restricted? Nature, 296, 311–313. 
Added by: Sarina (2010-01-09 12:53:55)   
Resource type: Journal Article
DOI: 10.1038/296311a0
BibTeX citation key: DuPasquier1982
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 Categories: Englisch = English
Keywords: Echsen = Lizards, Immunsystem = Immune System
Creators: Du Pasquier
Collection: Nature		 Views: 8/1027
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Abstract
Recent studies have revealed that lower vertebrates such as fish, amphibians and reptiles have an antibody repertoire that is much less diverse than that of mammals. It is suggested that the various mechanisms generating antibody diversity are the same in all vertebrates but that non-immunological parameters such as mode of ontogenetic development and cell cycle properties allow fewer somatic events in generating the antibody repertoire of cold-blooded vertebrates.
Added by: Sarina  
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