Licht-im-Terrarium: Literaturdatenbank
Licht-im-Terrarium: Literaturdatenbank |
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Setlow, R. B. (1974). The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. Proceedings of the National Academy of Sciences, 71(9), 3363–3366. Added by: Sarina (2009-04-18 19:37:56) |
| Resource type: Journal Article BibTeX citation key: Setlow1974 View all bibliographic details  |
Categories: Englisch = English Keywords: Ultraviolett = Ultraviolet Creators: Setlow Collection: Proceedings of the National Academy of Sciences |
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| Abstract |
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DNA is taken as the target for skin cancer induced by ultraviolet light, and the known data on the sensitivity of DNA as a function of wavelength are summarized. The sun's spectrum at the surface of the earth and the DNA action spectrum are used to calculate the carcinogenic effectiveness as a function of wavelength. The most effective wavelengths at 30°N latitude are <305 nm, and a 1% change in atmospheric ozone results in a 2% change in the effective dose of ultraviolet light. Since both the basic biological and physical data are reasonably precise, the major requirement for a quantitative evaluation of the dose response relation for ultraviolet-induced skin cancer in man is better epidemiological data to compare with data from animal models.
Added by: Sarina |